ABSTRACT
Introduction: Pregnancy is confronted with increased risk for COVID-19 since the expression of immune markers, realized the fact that the immune cells and cytokines, the virtuous understanding of the pathophysiology of the disease reduce maternal deaths. Pregnant women are enfeebled against the immune systems and are at added risk of contracting COVID-19. Indeed, they are at added risk of contracting COVID-19. The studies have proven the similarities between the COVID-19 and pregnancy regard to their immune system marked by a noticeable reduction in lymphocytes and raise in selected proinflammatory cytokines. Purpose: The study aims to conduct a review engine to enhance the knowledge on pathophysiological stirrings of condition in normal pregnancy and COVID-19, which are marked by decreased lymphocytes, NKG2A inhibitory receptors, and increased ACE2, IL-8, IL-10, and IP-10 project the risk for developing COVID-19 in pregnancy. To bring out the awareness on pregnancy vulnerability risk for COVID-19 and its complications. Method: This study is initiated with search engine reviewing previous studies correlating with various aspects of normal pregnancy COVID-19 pathophysiological aspects and COVID attack risk in pregnancy. This study probe through electronic databases such as PubMed, Medline, and Scopus databases using keywords such as Coronavirus Immune marker, Pregnancy Lymphocytes, Natural killer cells, a similar pat physiological condition in pregnancy, and COVID-19, Pregnancy vulnerability risk for COVID-19. Result: Analysed studies have given out fruitful information on pregnancy risk, the corona virus immune markers in pregnancy is seen with reduced lymphocytes, and increase proinflammatory cytokines that depict the similarity in the pathophysiological condition in pregnancy and COVID-19, pave up to pregnancy vulnerability for risk in COVID-19 contraction. Conclusion: This review analysis drawn informative tips for professionals that would be useful in educating patient as a part of preventive measure. © RJPT All right reserved.